Gordon Holmes Lecture: Gordon Holmes and the neurological heritage.

Adrenoleukodystrophy : phenotype , genetics , pathogenesis and therapy * Dedicated to the memory of Peter Moser

The occasion of the presentation of the eighth Gordon Holmes Yet I also feel a sense of sadness; the invitation to present the lecture came from the late Anita Harding who, such a short Lecture left me feeling both honoured and awed, as a result of my review of the Selected Papers of Gordon Holmes (Phillips time before her illness, gave me personal guidance and encouragement. In this lecture I ...

PNPLA6 mutations cause Boucher-Neuhauser and Gordon Holmes syndromes as part of a broad neurodegenerative spectrum.

Boucher-Neuhäuser and Gordon Holmes syndromes are clinical syndromes defined by early-onset ataxia and hypogonadism plus chorioretinal dystrophy (Boucher-Neuhäuser syndrome) or brisk reflexes (Gordon Holmes syndrome). Here we uncover the genetic basis of these two syndromes, demonstrating that both clinically distinct entities are allelic for recessive mutations in the gene PNPLA6. In five of s...

Introduction to Clinical Neurology

Sir Gordon Holmes.

FORTY MILES from Dublin at Castlebellingham on the coast of Co. Louth, Gordon Morgan Holmes was born in Dillon House on 22 February 1876. A scholar at Trinity College Dublin, he graduated B.A. in 1897, being senior moderator and gold medallist, and qualified in medicine the following year. After serving as a resident medical officer in the Richmond Asylum (now St. Brendan's Hospital), he studie...

Analytical solutions for the fractional Klein-Gordon equation

In this paper, we solve a inhomogeneous fractional Klein-Gordon equation by the method of separating variables. We apply the method for three boundary conditions, contain Dirichlet, Neumann, and Robin boundary conditions, and solve some examples to illustrate the effectiveness of the method.